30 August 2018, 16:00 CET - Ufa (Stadion Neftyanik)
FC Ufa (RUS) - Rangers FC (SCO)
Referee: Tobias Stieler (GER)
Assistant Referee 1: Mike Pickel (GER)
Assistant Referee 2: Christian Gittelmann (GER)
Fourth Official: Patrick Ittrich (GER)
UEFA Referee Observer: Goran Mihaljević (MNE)
UEFA Delegate: Boris Stankov (BUL)
30 August 2018, 16:00 CET - Astana (Astana Arena)
FC Astana (KAZ) - APOEL FC (CYP)
Referee: Jakob Kehlet (DEN)
Assistant Referee 1: Henrik Larsen (DEN)
Assistant Referee 2: Heine Sørensen (DEN)
Fourth Official: Michael Tykgaard (DEN)
UEFA Referee Observer: Asim Xudiyev (AZE)
UEFA Delegate: Adrian Ixari (MDA)
30 August 2018, 17:30 CET - Larnaca (AEK Aréna - Geórgios Karapatákis)
AEK Larnaca FC (CYP) - AS Trenčín (SVK)
Referee: Sergey Karasov (RUS)
Assistant Referee 1: Igor Demeshko (RUS)
Assistant Referee 2: Aleksey Lunov (RUS)
Fourth Official: Sergey Ivanov (RUS)
UEFA Referee Observer: Alexandru Deaconu (ROU)
UEFA Delegate: Karl Espen Eriksen (NOR)
30 August 2018, 18:30 CET - Copenhagen (Telia Parken)
FC København (DEN) - Atalanta BC (ITA)
Referee: Anastásios Sidirópoulos (GRE)
Assistant Referee 1: Polychrónis Kostarás (GRE)
Assistant Referee 2: Lázaros Dimitriádis (GRE)
Fourth Official: Anastásios Papapétrou (GRE)
UEFA Referee Observer: Jaap Uilenberg (NED)
UEFA Delegate: Wolfgang Thierrichter (AUT)
30 August 2018, 18:30 CET - Leipzig (Red Bull Arena)
RB Leipzig (GER) - FC Zorya Luhansk (UKR)
Referee: Danny Makkelie (NED)
Assistant Referee 1: Mario Diks (NED)
Assistant Referee 2: Hessel Steegstra (NED)
Fourth Official: Kevin Blom (NED)
UEFA Referee Observer: Matteo Simone Trefoloni (ITA)
UEFA Delegate: Kadri Jägel (EST)
30 August 2018, 19:00 CET - Netanya (Itztadion Ha'Ironi Netanya)
Maccabi Tel-Aviv FC (ISR) - Sarpsborg 08 FF (NOR)
Referee: Artur Manuel Ribeiro Soares Dias (POR)
Assistant Referee 1: Rui Licínio Barbosa Tavares (POR)
Assistant Referee 2: Paulo Alexandre dos Santos Soares (POR)
Fourth Official: Tiago Bruno Lopes Martins (POR)
UEFA Referee Observer: Nikolay Levnikov (RUS)
UEFA Delegate: Róbert Kispál (HUN)
30 August 2018, 19:00 CET - Nicosia (Stádio GSP)
Apollon Limassol FC (CYP) - FC Basel 1893 (SUI)
Referee: Ruddy Buquet (FRA)
Assistant Referee 1: Guillaume Debart (FRA)
Assistant Referee 2: Julien Pacelli (FRA)
Fourth Official: Amaury Delerue (FRA)
UEFA Referee Observer: Eyjólfur Ólafsson (ISL)
UEFA Delegate: Jaroslav Dudl (CZE)
30 August 2018, 19:00 CET - Molde (Aker Stadion)
Molde FK (NOR) - FC Zenit (RUS)
Referee: Carlos del Cerro Grande (ESP)
Assistant Referee 1: Juan Carlos Yuste Jiménez (ESP)
Assistant Referee 2: Abrahám Álvarez Cantón (ESP)
Fourth Official: Juan Martínez Munuera (ESP)
UEFA Referee Observer: Markus Nobs (SUI)
UEFA Delegate: Crawford Wilson (NIR)
30 August 2018, 19:00 CET - Cluj-Napoca (Stadionul Dr. Constantin Rădulescu)
CFR 1907 Cluj (ROU) - F91 Dudelange (LUX)
Referee: Davide Massa (ITA)
Assistant Referee 1: Filippo Meli (ITA)
Assistant Referee 2: Fabiano Preti (ITA)
Fourth Official: Maurizio Mariani (ITA)
UEFA Referee Observer: Fredy Fautrel (FRA)
UEFA Delegate: Rudolf Zavrl (SVN)
30 August 2018, 19:00 CET - Baku (Tofiq Bəhramov adına Respublika Stadionu)
Qarabağ FK (AZE) - FC Sheriff Tiraspol (MDA)
Referee: Aleksandar Stavrev (MKD)
Assistant Referee 1: Marjan Kirovski (MKD)
Assistant Referee 2: Dejan Kostadinov (MKD)
Fourth Official: Dimitar Mečkarovski (MKD)
UEFA Referee Observer: Johan Verbist (BEL)
UEFA Delegate: Jevgeņijs Miļevskis (LVA)
30 August 2018, 19:00 CET - Razgrad (Ludogorets Arena)
PFC Ludogorets 1945 (BUL) - FC Torpedo Kutaisi (GEO)
Referee: Mattias Gestranius (FIN)
Assistant Referee 1: Jan-Peter Aravirta (FIN)
Assistant Referee 2: Mikko Alakare (FIN)
Fourth Official: Antti Munukka (FIN)
UEFA Referee Observer: Mehmet Murat Ilgaz (TUR)
UEFA Delegate: Fívos Konstantinídis (CYP)
30 August 2018, 19:15 CET - Herning (MCH Arena)
FC Midtjylland (DEN) - Malmö FF (SWE)
Referee: Serdar Gözübüyük (NED)
Assistant Referee 1: Davie Goossens (NED)
Assistant Referee 2: Bas van Dongen (NED)
Fourth Official: Jeroen Manschot (NED)
UEFA Referee Observer: Kýros Vasáras (GRE)
UEFA Delegate: Claude Runavot (FRA)
30 August 2018, 20:00 CET - Istanbul (Vodafone Park)
Beşiktaş JK (TUR) - FK Partizan (SRB)
Referee: Ovidiu Alin Hațegan (ROU)
Assistant Referee 1: Octavian Șovre (ROU)
Assistant Referee 2: Sebastian Eugen Gheorghe (ROU)
Fourth Official: Sebastian Constantin Colțescu (ROU)
UEFA Referee Observer: Nikolay Ivanov (RUS)
UEFA Delegate: Kris Bellon (BEL)
30 August 2018, 20:15 CET - Skopje (Nacionalna Arena Filip II Makedonski)
KF Shkëndija (MKD) - Rosenborg BK (NOR)
Referee: Aliaksiej Kuĺbakoŭ (BLR)
Assistant Referee 1: Dzmitryj Žuk (BLR)
Assistant Referee 2: Alieh Maslianka (BLR)
Fourth Official: Dzianis Ščarbakoŭ (BLR)
UEFA Referee Observer: Gevorg Hovhannisyan (ARM)
UEFA Delegate: Gordon Pate (SCO)
30 August 2018, 20:30 CET - Bucharest (Arena Națională)
FC FCSB (ROU) - SK Rapid Wien (AUT)
Referee: Michael Oliver (ENG)
Assistant Referee 1: Stuart Burt (ENG)
Assistant Referee 2: Simon Bennett (ENG)
Fourth Official: Stuart Attwell (ENG)
UEFA Referee Observer: Zbigniew Przesmycki (POL)
UEFA Delegate: Anton Fagan (SCO)
30 August 2018, 20:30 CET - Brøndby (Brøndby Stadion)
Brøndby IF (DEN) - KRC Genk (BEL)
Referee: Gediminas Mažeika (LTU)
Assistant Referee 1: Vytautas Šimkus (LTU)
Assistant Referee 2: Vytenis Kazlauskas (LTU)
Fourth Official: Donatas Šimėnas (LTU)
UEFA Referee Observer: Edgar Steinborn (GER)
UEFA Delegate: Jacob Erel (ISR)
30 August 2018, 20:30 CET - Trnava (City Arena - Štadión Antona Malatinského)
FC Spartak Trnava (SVK) - NK Olimpija Ljubljana (SVN)
Referee: Luca Banti (ITA)
Assistant Referee 1: Alessandro Costanzo (ITA)
Assistant Referee 2: Giorgio Peretti (ITA)
Fourth Official: Marco Di Bello (ITA)
UEFA Referee Observer: Marinus Koopman (NED)
UEFA Delegate: Christian Kofoed (DEN)
30 August 2018, 20:45 CET - Bordeaux (Stade Matmut ATLANTIQUE)
FC Girondins de Bordeaux (FRA) - KAA Gent (BEL)
Referee: Jesús Gil Manzano (ESP)
Assistant Referee 1: Ángel Nevado Rodríguez (ESP)
Assistant Referee 2: Javier Martínez Nicolás (ESP)
Fourth Official: Alejandro José Hernández Hernández (ESP)
UEFA Referee Observer: Kóstas Kapitanís (CYP)
UEFA Delegate: Steve Stride (ENG)
30 August 2018, 20:45 CET - Burnley (Turf Moor)
Burnley FC (ENG) - Olympiakós FC (GRE)
Referee: Viktor Kassai (HUN)
Assistant Referee 1: György Ring (HUN)
Assistant Referee 2: Vencel Tóth (HUN)
Fourth Official: Sándor Andó-Szabó (HUN)
UEFA Referee Observer: Vladimír Medveď (SVK)
UEFA Delegate: Rainer Koch (GER)
30 August 2018, 21:00 CET - Glasgow (Celtic Park)
Celtic FC (SCO) - FK Sūduva (LTU)
Referee: Georgi Kabakov (BUL)
Assistant Referee 1: Martin Margaritov (BUL)
Assistant Referee 2: Diyan Valkov (BUL)
Fourth Official: Stanislav Todorov (BUL)
UEFA Referee Observer: Vlado Svilokos (CRO)
UEFA Delegate: Jeannette Good (FIN)
30 August 2018, 21:45 CET - Seville (Estadio Ramón Sánchez-Pizjuán)
Sevilla FC (ESP) - SK Sigma Olomouc (CZE)
Referee: István Kovács (ROU)
Assistant Referee 1: Vasile Florin Marinescu (ROU)
Assistant Referee 2: Mihai Ovidiu Artene (ROU)
Fourth Official: Ionuț Marius Avram (ROU)
UEFA Referee Observer: Elmir Pilav (BIH)
UEFA Delegate: Francesca Sanzone (ITA)
